SERUM METABOLOMICS REVEALED THE DIFFERENTIAL METABOLIC PATHWAY IN CALVES WITH SEVERE CLINICAL DIARRHEA SYMPTOMS

Serum Metabolomics Revealed the Differential Metabolic Pathway in Calves with Severe Clinical Diarrhea Symptoms

The complex etiology, higher morbidity and mortality, poor prognosis, and expensive cost of calf diarrhea have made it a catastrophic disease in the dairy industry.This study aims to assess the biomarkers in calves with diarrhea and to predict the biomarkers related to the pathway.As subjects, nine calves with diarrhea and nine healthy calves were

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Altered Metabolic Phenotypes and Hypothalamic Neuronal Activity Triggered by Sodium-Glucose Cotransporter 2 Inhibition

Background Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are currently used to treat patients with diabetes.Previous studies have demonstrated that treatment with SGLT-2 inhibitors is accompanied by altered metabolic phenotypes.However, it has not been investigated whether the hypothalamic circuit participates in the Soft Toy development of th

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